I use mutiple screens for one of my courses at uni, we have a CRT as the main screen and a LCD one as the secondary screen. When I first saw the setup I just thought it was another example of the UNi spending money for the sake of it, but it actually comes in REALLY handy, especially when writing essays (with say websites as a reference), doing photoshop work, websites etc. As far as I know most video cards these days have what is required to use the two monitors. But just in case, the Uni is using GeForce4 Ti4200 cards in there PCs, runing WinXP Pro. And as far as I'm aware no other special hardware is used.